On endothelial cells and COVID.

What are endothelial cells? They are the cells lining the blood vessels.

"If it were not for endothelial cells extending and remodeling the network of blood vessels, tissue growth and repair would be impossible. It is hoped that by blocking the formation of new blood vessels through drugs that act on endothelial cells, it may be possible to block the growth of tumors." (They want to research how to keep endothelial cells from repairing themselves.) https://www.ncbi.nlm.nih.gov/books/NBK26848/

Now take a look at some studies about COVID and endothelial cells.

SARS-COV-2 spike protein makes the virus primarily a vascular disease. Salk researchers collaborated with scientists at the University of California San Diego on the paper, including co-first author Jiao Zhang and co-senior author John Shyy, among others. Scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented. Other authors on the study are Yuyang Lei and Zu-Yi Yuan of **Jiaotong University in Xi'an, China**; Cara R. Schiavon, Leonardo Andrade, and Gerald S. Shadel of Salk; Ming He, Hui Shen, Yichi Zhang, Yoshitake Cho, Mark Hepokoski, Jason X.-J. Yuan, Atul Malhotra, Jin Zhang of the **University of California San Diego**; Lili Chen, Qian Yin, Ting Lei, Hongliang Wang and Shengpeng Wang of Xi'an **Jiatong University Health Science Center in Xi'an, China**. https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/ Backup of article: https://archive.ph/hgjK4 The paper: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902 Backup of paper: https://archive.ph/fOrV3 DOI: 10.1161/CIRCRESAHA.121.318902

Prestigious Salk Institute says it's the spike proteins from the brand new, untested COVID-19 vaccine that is causing so many problems. Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease. In the new study, the researchers created a "pseudovirus" that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model--proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls. https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/ Backup at: https://archive.ph/hgjK4 The paper: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902 available as PDF or EPUB.

Study: "SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2". COVID-19 damages cell mitochondria, you may never recover your energy level. https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.318902

Further unification of spike protein microvascular disease and tauopathy: TLR-2. I believe I can now fully explain why Tauopathies are occurring in association with SARS-CoV-2 and its Spike Protein. Radiation PERMANENTLY alters NF-kB expression and reprograms endothelial cells resulting in vascular disease. The very same activation also increases the effects of ALL risk factors associated with Alzheimer’s Disease. (What's a better way to collapse a medical system than with incurable brain disease.) Of course, SARS-CoV-2 is NOT radiation. However the Spike Protein MIMICKS THE EFFECTS OF RADIATION EXACTLY including activation of NF-kB via TLR-2. This also explains why the elderly are far more at risk of IMMEDIATE severe disease and death. Young mice have virtually NO NF-kB levels in their Hypothalamus! With links to studies. Treatment in the comments. NAC dissolves blood clots but also amyloid plaque. https://wmcresearch.substack.com/p/further-unification-of-spike-protein?utm_source=email

Why the increasingly lethal damage (from SARS-COV-2/COVID-19 and the vaccines) is so difficult to find and why it can take so long to manifest: the spike protein, endothelial assault, vasculitis, and the trash compactor scene from Star Wars. "Vasculitis is a deadly serious disease. Once a blood vessel is affected by vasculitis, it is NEVER the same. It will suffer permanent damage." https://wmcresearch.substack.com/p/why-the-increasingly-lethal-damage

Spike protein induced endothelin damage. SPED (Spike Protein Endothelial Disease) as cause of the vast majority of the recent sudden cardiac deaths: destruction of the brainstem and the cardiac microvasculature. With supporting studies. I believe there is another mechanism by which the Spike Protein can cause sudden cardiac death. The immune complexes of the spike protein are being deposited into the brainstem causing structural damage and its dysfunction. https://wmcresearch.substack.com/p/sped-spike-protein-endothelial-disease?utm_source=%2Finbox&utm_medium=reader2

Is the spike protein transforming the vasculature into "tumor blood vessels?" In 14 out of 16 autopsies for COVID-19 victims, a startling finding was made. Glomeruloid-like microscopic foci and/or coalescent vascular proliferations measuring up to 2 cm were present in the lung of 14 out of 16 autopsied patients. These lesions expressed CD31, CD34 and vascular endothelial cadherin (VE-Cadherin). We have the transformation of healthy endothelium into that of tumor endothelium. With links to more studies. https://wmcresearch.substack.com/p/is-the-spike-protein-transforming?utm_source=%2Finbox&utm_medium=reader2

SPED and the observed cachexia (General physical wasting and malnutrition usually associated with chronic disease) in long COVID. Building the SPED hypothesis as the foundation of Long COVID and SADS pathology. **The spike protein causes the endothelial cells to secrete THE VERY SAME CYTOKINES THAT TUMORS DO.** https://wmcresearch.substack.com/p/sped-and-the-observed-cachexia-in?utm_source=%2Finbox&utm_medium=reader2